William H. Powell was the last artist to be commissioned by the Congress for a painting in the Rotunda. His dramatic and brilliantly colored canvas shows Spanish conqueror and explorer Hernando DeSoto, riding a white horse, the first European to view the Mississippi River, in 1541. As De Soto and his troops approach, the Native Americans in front of their tepees watch, and a chief holds out a peace pipe. In the foreground is a jumble of weapons and soldiers, suggesting the attack they had suffered shortly before. To the right, a monk prays as a crucifix is set in the ground.
SOURCE